Vladimir Salmin
National Research Nuclear University, National Research University «Moscow Institute of Physics and Technology», Bauman Moscow State Technical University, Moscow, Russia.
Professor Vladimir V. Salmin, PhD, Dr.Sci.
National Research University «Moscow Institute of Physics and Technology» (MIPT), (Moscow, Russia), National Research Nuclear University (MEPHI), (Moscow, Russia), Bauman Moscow State Technical University (BMSTU), (Moscow, Russia)
There are numerous methods of optical diagnostics in biological objects, incl. fluorescence spectroscopy in vivo. Minimally invasive and non-invasive optical methods are often used for the assessment of tissue hypoxia, inflammation, and metabolic alterations. In the brain, autofluorescence spectroscopy provides information on energy metabolism, accumulation of advanced glycation end products, cell-to-cell communication, changes in intracranial tension, development of hypoxia and ischemia, blood-brain barrier breakdown, pharmacokinetic and pharmacodynamic effects of drugs.